The victory improved the fifth-ranked Rebels to 13-4 overall and 2-0 in conferece play, while MSU fell to 7-9 and 0-2.
In a nip-and-tuck affair, the Bulldogs actually battled back to take a 6-5 lead in the home half of the sixth inning.
Ole Miss evened the game at 6-6 with a single run in the seventh inning. An inning later, the Rebels broke open the game with four runs. The tie was broken on a three-run double down the left field line by Michael Guerrero. The Rebels closed the scoring with an insurance run in the ninth inning.
MSU grabbed a 1-0 lead on an RBI single by Jason Nappi in the first inning.
Ole Miss took a 3-1 advantage with three runs in its half of the third inning. Evan Button reached as a hit batsman. Brett Basham followed with a double to left center. Jordan Henry lined a two-run single to center field. After a double by Cody Overbeck, a sacrifice fly by Guerrero closed that inning.
The Bulldogs tied the game 3-3 in their half of the third inning with back to back home runs by Nappi and Cody Freeman. For Nappi, it was his fourth home run of the year, while Freeman has now hit two round-trippers.
MSU then grabbed a 4-3 lead in the fourth inning on an RBI single by Mark Goforth. The Bulldogs led 6-5 in the sixth inning thanks to singles by Russ Sneed, Jet Butler and Goforth. Butler drove Sneed home, while Collins hit a groundout, scoring Butler.
Ole Miss finished with 12 hits. Logan Power led the offensive attack with three hits. Overbeck and Henry each had multiple hits. Overbeck has now hit safely in all 17 games this season for Ole Miss.
The Bulldogs finished with 11 hits, giving MSU 14 games with double digit hits this season. Nappi, Freeman, Sneed and Goforth each had multiple hits for the Bulldogs.
Scott Bittle (1-0) pitched the final four innings to earn the win. Bittle allowed two hits and one run (earned), with five strikeouts and one walk. Cody Satterwhite started for the Rebels.
John Lalor (0-1) took the loss in middle relief for the Bulldogs. Lalor pitched two innings, allowing two hits and four runs (three earned). Justin Pigott started on the mound for the Bulldogs and lasted 2-2/3 innings. Greg Houston followed Pigott, while Jared Wesson followed Lalor.
MSU and Ole Miss complete their three-game weekend series with a 1:30 p.m. start Sunday. The Bulldogs will throw sophomore right-hander Ricky Bowen (1-2, 10.20 ERA), while the Rebels will throw sophomore left-hander Nathan Baker (1-1, 4.11). The contest will be shown regionally by Comcast Sports Southeast.